Pevaryl (Econazole) 1% Foaming Solution – 3 × 10 g Sachets
Rapid 3‑Day Topical Antifungal for Full‑Body Fungal Conditions

Active Ingredient & Other Names
Econazole nitrate 1% w/w — a broad-spectrum imidazole-
Common formulations include Pevaryl cream, solution, powder, and Ecoza foam

Drug Classification
Topical imidazole antifungal

Classified as OTC/farmacy-only, regulated as a medical device (foam) or medicinal product based on jurisdiction

Econazole disrupts fungal cell membranes by inhibiting lanosterol 14α‑demethylase, blocking ergosterol biosynthesis and causing fungal cell death

Indications & Uses
Treats common dermatophyte and yeast infections including:

Tinea pedis (athlete’s foot) – both interdigital and plantar

Tinea cruris (jock itch), tinea corporis (ringworm), tinea versicolor

Cutaneous candidiasis (e.g., yeast infections of skin)

Dosage & Administration
Foaming Solution (3-day regimen)

Evenings 1–3: Shower, apply foam to wet skin/scalp, rub for 3–5 minutes; do not rinse.

Next morning: shower as usual.

Repeat full 3-day treatment at 1 month and 3 months to reduce relapse risk

If incomplete response after 2 weeks: consult a healthcare provider; microbiological testing may be warranted .

Administration Tips & Precautions
Avoid eyes, mucous membranes, and contraceptive diaphragms (rubber may degrade)

Foam is flammable; avoid open flames or smoking during application
Store at room temperature; do not freeze or expose to heat above 25–30 °C

Common (≤1%): Mild burning, itching, stinging, redness, dryness at application site
Rare/Serious: Allergic reactions (hives, facial swelling, respiratory distress); discontinue and seek medical attention if these occur
Discontinue if persistent irritation or hypersensitivity emerges

Not for use on genital mucosa without medical advice; use separate treatments for such zones

In cases of infant or severe infections, consult a physician before use

If no improvement after 1 week, seek medical evaluation

Warfarin: topical econazole can potentiate anticoagulant effects if applied over large areas or under occlusion—monitor INR

Rare systemic absorption minimizes interactions with other medications

Use in Special Populations
Pregnancy: Category A (AU) or C (foam); use only if benefits justify risks

Breastfeeding: Unknown excretion in milk; use with caution

Children: Foam evaluated in 12–17-year-olds with similar safety profile


FAQs
Q1. How quickly does Pevaryl foam work?
A: Visible improvement often begins within a week; full treatment includes 3-day course plus repeat at one-month intervals to prevent relapse .

Q2. Is it flammable?
A: Yes — avoid flames during use due to the alcohol-based propellant .

Q3. Can I treat athlete’s foot between toes?
A: Yes — foam is indicated for interdigital tinea pedis; apply once daily for 4 weeks if needed .

Q4. What if symptoms recur?
A: Repeat the 3-day regimen at one and three months after the initial course; consult a healthcare provider if relapse persists .

Q5. Can I combine with antifungal creams?
A: Yes — topical combination therapy is acceptable. Monitor for irritation.

What is Pevaryl Foaming Solution used for?
Pevaryl (econazole) 1% foaming solution is applied to wet skin or scalp for 3 consecutive nights to rapidly treat fungal infections like ringworm, jock itch, athlete’s foot, scalp tinea, and pityriasis versicolor. Repeat at 1 and 3 months to prevent relapse.